Tuberculosis has affected man kind from very ancient times. Man has continued to live in a state of uneasy equilibrium which can be easily disturbed in favor of the disease. Neither man nor the bacillus has shown sufficiently strong supremacy to win this battle. It is as old as mankind. Soma, the Moon God ,suffered from “Tuberculosis”. It is mentioned in Yajurveda. Hymn in Rig Ved is there to cure Yakhma. Recent Data reveals that TB existed 40,000 years ago, which corresponds to the period subsequent to the expansion of Homo sapiens out of Africa. Its existence is evident in Neolithic manand , Mummies of 5000 BC. Sushrut (600 BC) described the disease and opined difficult to cure. Hippocrates (460-377 BC ) opined , there is no cure for the disease. Raj yaksma (India), Phthisis (Greek), consumption (Latin) and the White Plague are all terms used to refer to Tuberculosis through out history. Treatments varied from good food, clean air , herbs, mantra, tantra to touching of the king’s feet on Scrofula, ( gland TB on the neck).